The Therapeutic Effects of Goreisan, a Traditional Japanese Herbal Medicine, on Lower-Limb Lymphedema after Lymphadenectomy in Gynecologic Malignancies: A Case Series Study

Table 3

Improvement in status of LLL from pretreatment to posttreatment.

Reduction	Total population (n = 19)	CDT group (n = 8)	CDT-G group (n = 11)	value
BMI (kg/m^2) (mean, 95% CI)	−0.24 (−0.85 to 0.38)	0.19 (−0.74 to 1.12)	−0.55 (−1.34 to 0.24)	0.2183
Body mass (kg) (mean, 95% CI)	−0.62 (−2.22 to 0.97)	0.46 (−1.98 to 2.90)	−1.42 (−3.50 to 0.66)	0.2331
ECW/TBW (mean, 95% CI)
Total body	−0.0031 (−0.0059 to −0.0004)	−0.0001 (−0.0039 to 0.0037)	−0.0053 (−0.0086 to −0.0021)	0.0417
Affected lower limb	−0.0037 (−0.0077 to 0.0003)	0.0007 (−0.0041 to 0.0056)	−0.0069 (−0.0126 to −0.0012)	0.0423
Unaffected lower limb	−0.0025 (−0.0061 to 0.0010)	−0.0001 (−0.0055 to 0.0052)	−0.0042 (−0.0089 to 0.0003)	0.2324
Estimated volume (mL) (mean, 95% CI)
Affected lower limb	15.73 (−245.27 to 276.73)	141.65 (−265.3 to 548.57)	−75.84 (−422.9 to 271.18)	0.4028
Unaffected lower limb	−63.63 (−313.92 to 186.66)	−130.40 (−526.5 to 265.65)	−15.07 (−352.8 to 322.69)	0.6461

LLL, lower-limb lymphedema; CDT, complex decongestive therapy; CDT-G, combination of complex decongestive therapy and goreisan; BMI, body mass index; CI, confidence interval; ECW/TBW, ratio of extracellular water to total body water.