Evaluation of Antidiabetic Activity of Ajuga integrifolia (Lamiaceae) Root Extract and Solvent Fractions in Mice

Table 1

Hypoglycemic activity of AIR crude extract in normoglycemic mice.

Blood glucose level (mg/dl)
Group	0 hr	1 hr	2 hr	4 hr	6 hr
DW10 mg/kg	70.60 ± 0.707	69.40 ± 1.208	71.20 ± 2.131	72.40 ± 1.860	68.60 ± 1.304
AIRE100 mg/kg	74.00 ± 2.449	75.40 ± 2.135	74.80 ± 1.503	69.20 ± 2.634	67.80 ± 2.088
AIRE200 mg/kg	69.60 ± 1.208	69.60 ± 1.503	70.60 ± 0.872	67.20 ± 0.860	68.40 ± 1.581
AIRE400 mg/kg	72.60 ± 1.568	72.90 ± 1.001	73.80 ± 2.267	69.10 ± 1.778	66.20 ± 1.631
GLC 5 mg/kg	72.40 ± 1.560	55.80 ± 2.985	51.60 ± 2.272^a1b1c1d1β1	43.60 ± 1.568^AzBxCxDxβy	36.60 ± 1.965^AzByCyDyβz

N = 6 for each treatment; each value is presented in mean ± SEM. ^ACompared to the negative control; ^βcompared to the baseline blood glucose level; ^Bcompared to 100 mg/kg AIRE; ^Ccompared to 200 mg/kg AIRE; ^Dcompared to 400 mg/kg AIRE. . AIRE, Ajuga integrifolia root extract; DW, distilled water; GLC, glibenclamide.