Evaluation of Antidiabetic Activity of Ajuga integrifolia (Lamiaceae) Root Extract and Solvent Fractions in Mice

Table 2

Oral glucose tolerance test of crude root extract of Ajuga integrifolia in the oral glucose loaded mice model.

Blood glucose level (mg/dl)
Group	0 min	30 min	60 min	120 min
DW10 ml/kg	82.8 ± 2.634	214.6 ± 5.802^βz	157.8 ± 4.164^βz3x	113.8 ± 4.974^3z
AIRE100 mg/kg	87.6 ± 2.249	211.2 ± 4.994^βz	148.8 ± 4.944^βz3y	89.8 ± 2.437^Ax3z
AIRE200 mg/kg	82.6 ± 2.731	205.6 ± 5.820^Axβz	148.6 ± 5.573^Axβz3y	88 ± 2.530 5^AxBx3z
AIRE400 mg/kg	73.8 ± 1.625	212.6 ± 7.852^Axβz	142.8 ± 3.105^Axβz3z	79.6 ± 4.98^AyBxCx3z
GLC5 mg/kg	76 ± 2.408	154.4 ± 7.461^AyByCyDyβz	73.6 ± 5.112^AzByCyDyβz3y	61.8 ± 6.715^AxBxCxDxβz3z

N = 6 for each treatment; each value is presented in mean ± SEM. ^ACompared to the negative control; ^βcompared to the baseline blood glucose level; ^Bcompared to 100 mg/kg AIRE; ^Ccompared to 200 mg/kg AIRE; ^Dcompared to 400 mg/kg AIRE; ³compared to the blood glucose level at 30 minute. . DW, distilled water; AIRE, Ajuga integrifolia root extract; GLC, glibenclamide. Time in minute indicates after oral glucose load.