Evaluation of Antidiabetic Activity of Ajuga integrifolia (Lamiaceae) Root Extract and Solvent Fractions in Mice

Table 3

Effect of single dose AIRE on hyperglycemia in STZ-induced diabetic mice.

Blood glucose level (mg/dl)
Group	0 hr	2 hr	4 hr	6 hr	8 hr
DW10 ml/kg	391.6 ± 2.249	386.2 ± 5.877	395 ± 1.581	393.8 ± 1.497	395.4 ± 1.600
AIRE100 mg/kg	416 ± 27.817	382 ± 19.514	365 ± 10.124	369 ± 9.894	253 ± 9.160^Axβy
AIRE200 mg/kg	377.4 ± 21.970	358.4 ± 18.10	343.6 ± 16.336	339.2 ± 12.816	317.6 ± 10.671^AxBxβy
AIRE400 mg/kg	393 ± 11.176	368.6 ± 14.038	362 ± 17.283	349.2 ± 19.523	313.4 ± 8.897^AxBxβy
GLC mg/kg	376.4 ± 8.698	282.6 ± 2.960^Axβy	197.2 ± 4.224^Axβz	178.2 ± 2.653^AyBxCxDxβz	168 ± 3.975^az bxcxdxβz

N = 6 for each treatment; each value is presented in mean ± SEM. ^ACompared to the negative control; ^βcompared to the baseline blood glucose level; ^Bcompared to 100 mg/kg AIRE; ^Ccompared to 200 mg/kg AIRE; ^Dcompared to 400 mg/kg AIRE. . DW, distilled water; GLC, glibenclamide; AIRE, Ajuga integrifolia root extract.