Evaluation of Antidiabetic Activity of Ajuga integrifolia (Lamiaceae) Root Extract and Solvent Fractions in Mice

Table 5

The effect of repeated daily doses of Ajuga integrifolia root extract on bodyweight in STZ-induced diabetic mice.

Bodyweight (gram)
Group	Before induction	Baseline	7 days after t/t	14 days after t/t
DW 10 ml/kg	29.80 ± 1.251	27.31 ± 1.140	25.75 ± 1.900	23.09 ± 1.371
AIRE 100 mg/kg	28.25 ± 1.89	26.84 ± 2.331	25.92 ± 2.170	24.74 ± 1.382
AIRE 200 mg/kg	27.92 ± 2.71	25.62 ± 2.120	26.53 ± 1.070^Axβynx	26.33 ± 1.080^Ayβznx
AIRE400 mg/kg	28.10 ± 2.092	26.90 ± 1.220	27.25 ± 1.320^Axβynx	27.6 ± 1.684^Ayβznx
GLC5 mg/kg	26.80 ± 1.631	25.71 ± 1.933	27.48 ± 2.124^Ayβznx	27.90 ± 2.153^Azβznx
Normal control	30.40 ± 2.360	29.53 ± 2.730	30.10 ± 1.552	29.53 ± 1.447

N = 6 for each treatment; each value is presented in mean ± SEM. ^ACompared to the diabetic control; ^βcompared to the baseline blood glucose level; ^Bcompared to 100 mg/kg AIRE; ^Ccompared to 200 mg/kg AIRE; ^Dcompared to 400 mg/kg AIRE; ⁿcompared to normal control. . DW, distilled water; GLC, glibenclamide; AIRE, Ajuga integrifolia root extract; t/t, treatment.