Evaluation of Antidiabetic Activity of Ajuga integrifolia (Lamiaceae) Root Extract and Solvent Fractions in Mice

Table 7

The activity of repeated daily doses of aqueous fraction of AIRE against hyperglycemia in STZ-induced diabetic mice.

Blood glucose level (mg/dl)
Group	Baseline BGL	BGL at 7^th day	BGL at 14^th day	7^th day R (%)	14^th day R (%)
DW10 ml/kg	391.6 ± 5.030	429.2 ± 33.041	489.2 ± 43.101	−9.58	−24.85
AQA100 mg/kg	415.8 ± 62.311	379.19 ± 25.203^Axβxnx	372.8 ± 26.329^Axβxnx	7.93	9.43
AQA200 mg/kg	375.4 ± 52.681	311.20 ± 35.181^AyBxβxnx	296.2 ± 36.093^AyBxβxnx	16.76	20.52
AQA400 mg/kg	393 ± 24.990	306.21 ± 20.584^AyBxβxnx	286 ± 21.91^AyBxβxnx	22.13	23.89
GLC5 mg/kg	376.4 ± 19.45	146.6 ± 16.607^AyBzCxDy βynx	135.2 ± 6.907 ^AzBzCyDyβzn1	61.3.0	64.10
Normal control	82.6 ± 4.231	81.9 ± 2.890	82.8 ± 1.931	0.840	−0.20

N = 6 for each group; each value is presented in mean ± SEM. ^ACompared to diabetic control; ^βcompared to baseline; ^Bcompared to 100 mg/kg; ^Ccompared to 200 mg/kg; ^Dcompared to 400 mg/kg; ⁿcompared to normal control. . GLC, glibenclamide; AQA, aqueous; DW, distilled water; R, reduction.