Evaluation of Antidiabetic Activity of Ajuga integrifolia (Lamiaceae) Root Extract and Solvent Fractions in Mice

Table 8

Effect of repeated daily doses of aqueous fraction of AIR on bodyweight in STZ-induced diabetic mice.

Bodyweight (gram)
Group	Before induction	Baseline	After 7 days	After 14 days
DW10 ml/kg	29.34 ± 1.516	26.4 ± 0.894	23 ± 2.915^GxβxnxBxCxDx	21.2 ± 1.781^GxβxnxBxCxDx
AIRE100 mg/kg	30.8 ± 3.271	26.6 ± 2.074	25.3 ± 1.732	26.2 ± 1.924
AIRE200 mg/kg	27 ± 2.739	24.2 ± 1.924	24.8 ± 2.550^βx	25.4 ± 2.387^βx
AIRE400 mg/kg	27.4 ± 2.074	25.3 ± 1.673	25.6 ± 1.817^βx	26.9. ± 1.789^βx
GLC5 mg/kg	28.4 ± 4.615	26.8 ± 1.789	27.84 ± 1.483	28.7 ± 1.516^βx
Normal control	28.2 ± 3.033	28.9 ± 2.302	29 ± 2.121	29.4 ± 2.074

N = 6 for each group; each value is presented in mean ± SEM. ^GCompared to 5 mg/kg GLC; ^βcompared to the baseline value; ^Bcompared to 100 mg/kg AIRE; ^Ccompared to 200 mg/kg; ^Dcompared to 400 mg/kg AIRE; ⁿcompared to normal control. . AIRE, Ajuga integrifolia root extract; GLC, glibenclamide; DW, distilled water.