Acute Wound Healing Potential of Marine Worm, Diopatra claparedii Grube, 1878 Aqueous Extract on Sprague Dawley Rats

Figure 3

Hematoxylin & Eosin (H & E) staining of granulation healing tissue of Sprague Dawley rats treated with different treatment groups on day 14 after wounding. Seven groups were tested which were (a) untreated group, polychaete ointment (PO) with concentration of (b) 0.1%, (c) 0.5%, and (d) 1.0%, (e) cetomacrogol emulsifying ointment (negative control), (f) gamat 15%, and (g) acriflavine 0.1%. Smaller granulation tissue with denser collagen fibres and more new capillaries formation was seen in 1.0% PO than other treatments. E = epidermis, S = scar/granulation tissue, N = normal dermis, H = hair follicle, B = blood vessel. 40X magnification.

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