Acute Wound Healing Potential of Marine Worm, Diopatra claparedii Grube, 1878 Aqueous Extract on Sprague Dawley Rats

Figure 4

Masson’s trichrome (MT) staining of granulation healing tissue of Sprague Dawley rats treated with different treatment groups at day 14 after wounding. Seven groups were tested which were (a) untreated group, polychaete ointment (PO) with concentration of (b) 0.1%, (c) 0.5%, and (d) 1.0%, (e) cetomacrogol emulsifying ointment (negative control), (f) gamat 15%, and (g) acriflavine 0.1%. New collagen formation was seen as FC and matured collagen as CC. More new collagen depositions in meshwork formation appeared in 1.0% PO. S = scar/granulation tissue, E = epidermis, CC = coarse collagen, FC = fine collagen, H = hair follicle. 40X magnification.

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