Research Article

Acute Wound Healing Potential of Marine Worm, Diopatra claparedii Grube, 1878 Aqueous Extract on Sprague Dawley Rats

Table 2

Skin irritation score after different concentrations of polychaete ointment (PO) applied on intact skin over period of time. Concentrations of PO were 0.1%, 0.5%, and 1.0%. Cetomacrogol emulsifying ointment was used as negative control. No signs of skin irritation (oedema and erythema) were observed for all the tested ointments.

Skin reactionObservation time (hr)TreatmentTotal score
Negative control0.1% PO0.5% PO1.0% PO

Erythema formation100000
2400000
4800000
7200000

Oedema formation100000
2400000
4800000
7200000