<i>Bupleurum chinense</i> Polysaccharide Improves LPS-Induced Senescence of RAW264.7 Cells by Regulating the NF-<i>κ</i>B Signaling Pathway

<div>Effects of BCP on macrophage-aging induced by LPS. (a) SA-<i>β</i>-gal staining; (b) SA-<i>β</i>-gal-positive cell count analysis; (c) DAPI staining; (d) DAPI fluorescence intensity analysis; (e) electrophoresis images of p53, p16, phosphorylated p53 and p16, and <i>β</i>-actin protein; (f) p-p53/<i>β</i>-actin, p53/<i>β</i>-actin, p-p16/<i>β</i>-actin, and p16/<i>β</i>-actin column charts. Results are presented as means ± SD. <span class="nowrap"><svg height="15.3614pt" id="M30" style="vertical-align:-3.833899pt" version="1.1" viewbox="-0.0498162 -11.5275 64.9458 15.3614" width="64.9458pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0091,0,0,-0.0091,0,-5.741)"><path d="M457 455H370L403 612H360L326 455H218L252 612H210L175 455H77L68 394H161L132 257H31L20 196H117L77 19H120L159 196H268L230 19H272L311 196H402L412 257H325L355 394H447L457 455ZM313 394L283 257H175L204 394H313Z"></path></g><g transform="matrix(.0091,0,0,-0.0091,4.432,-5.741)"><path d="M457 455H370L403 612H360L326 455H218L252 612H210L175 455H77L68 394H161L132 257H31L20 196H117L77 19H120L159 196H268L230 19H272L311 196H402L412 257H325L355 394H447L457 455ZM313 394L283 257H175L204 394H313Z"></path></g><g transform="matrix(.0091,0,0,-0.0091,8.863,-5.741)"><path d="M457 455H370L403 612H360L326 455H218L252 612H210L175 455H77L68 394H161L132 257H31L20 196H117L77 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Evidence-Based Complementary and Alternative Medicine

fig4

Figure 4

Figure 4: <i>Bupleurum chinense</i> Polysaccharide Improves LPS-Induced Senescence of RAW264.7 Cells by Regulating the NF-<i>κ</i>B Signaling Pathway 

Evidence-Based Complementary and Alternative Medicine

Bupleurum chinense Polysaccharide Improves LPS-Induced Senescence of RAW264.7 Cells by Regulating the NF-κB Signaling Pathway

Figure 4