Rhein Suppresses Neuroinflammation via Multiple Signaling Pathways in LPS-Stimulated BV2 Microglia Cells

Figure 3

Effects of Rhein on iNOS, IL-6, IL-10, and IL-12 in LPS-stimulated BV2 cells. The cells were untreated (control) or pretreated with Rhein/DMSO for 30 min, followed by LPS stimulation (1 μg/mL) for 48 h. (a-d) Effects of Rhein on supernatants iNOS, IL-6, IL-10, and IL-12 in LPS-stimulated BV2 cells, the amounts of supernatants were assayed by ELISA. Data represent the mean ± SEM of three independent experiments. , , and .

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