Research Article
Probe into the Target and Mechanism of Jianpi Xiaoke Prescription for Treating Type 2 Diabetes Mellitus through miRNA Expression Profiling
Table 3
Comparison of 7 predicted therapeutic targets (log2FC ≥ 1 or ≤ −1, and
).
| Gene name | Family | MIR | Model/control | JPXK/model | Log2FC | value | Log2FC | value |
| miR-3473 | No [8] | MIMAT0024853 | −3.37 | 0.000 | 1.39 | 0.019 | miR-547-3p | mir-547 | MIMAT0012851 | −1.68 | 0.002 | 1.32 | 0.030 | miR-1-3p | mir-1 | MIMAT0003125 | −1.33 | 0.018 | 4.15 | 0.000 | miR-181d-5p | mir-181 | MIMAT0005299 | −1.19 | 0.044 | 1.21 | 0.036 | miR-206-3p | mir-1 | MIMAT0000879 | −1.15 | 0.049 | 4.14 | 0.000 | miR-135a-5p | mir-135 | MIMAT0000841 | 2.00 | 0.003 | −1.79 | 0.001 | miR-215 | mir-192 | MIMAT0003118 | 2.58 | 0.002 | −1.17 | 0.033 |
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