Research Article

A Network Pharmacology-Based Study on the Anti-Lung Cancer Effect of Dipsaci Radix

Table 2

The top 10 most significant terms in GO enrichment analyses.

IdDescription adjustCount

Biological processes
GO:0043401Steroid hormone-mediated signaling pathway8.30E 1929
GO:0071383Cellular response to steroid hormone stimulus1.24E 1832
GO:0048545Response to steroid hormone1.05E 1737
GO:0009755Hormone-mediated signaling pathway3.41E 1729
GO:0006367Transcription initiation from RNA polymerase II promoter5.08E 1424
GO:0030522Intracellular receptor signaling pathway1.30E 1328
GO:1901652Response to peptide2.44E 1336
GO:0046777Protein autophosphorylation1.46E 1224
GO:0072593Reactive oxygen species metabolic process5.02E 1226
GO:0000302Response to reactive oxygen species9.15E 1224

Molecular functions
GO:0004879Nuclear receptor activity2.07E 2421
GO:0098531Transcription factor activity and direct ligand-regulated sequence-specific DNA binding2.07E 2421
GO:0003707Steroid hormone receptor activity2.07E 2422
GO:0004713Protein tyrosine kinase activity5.32E 1622
GO:0033293Monocarboxylic acid binding2.94E 1013
GO:0031406Carboxylic acid binding1.41E 0919
GO:0043177Organic acid bindings1.47E 0919
GO:0004714Transmembrane receptor protein tyrosine kinase activity1.45E 0710
GO:0004715Nonmembrane spanning protein tyrosine kinase activity1.52E 079
GO:0004175Endopeptidase activity1.52E 0722

Cellular components
GO:0031983Vesicle lumen8.41E 0823
GO:0060205Cytoplasmic vesicle lumen1.35E 0722
GO:0045121Membrane raft1.35E 0721
GO:0098857Membrane microdomain1.35E 0721
GO:0034774Secretory granule lumen1.69E 0721
GO:0098589Membrane region1.69E 0721
GO:0101002Ficolin-1-rich granule7.38E 0513
GO:0031012Extracellular matrix2.70E 0420
GO:1904813Ficolin-1-rich granule lumen2.70E 0410
GO:0031256Leading edge membrane2.70E 0411