Research Article
A Network Pharmacology-Based Study on the Anti-Lung Cancer Effect of Dipsaci Radix
Table 2
The top 10 most significant terms in GO enrichment analyses.
| Id | Description | adjust | Count |
| Biological processes | GO:0043401 | Steroid hormone-mediated signaling pathway | 8.30E − 19 | 29 | GO:0071383 | Cellular response to steroid hormone stimulus | 1.24E − 18 | 32 | GO:0048545 | Response to steroid hormone | 1.05E − 17 | 37 | GO:0009755 | Hormone-mediated signaling pathway | 3.41E − 17 | 29 | GO:0006367 | Transcription initiation from RNA polymerase II promoter | 5.08E − 14 | 24 | GO:0030522 | Intracellular receptor signaling pathway | 1.30E − 13 | 28 | GO:1901652 | Response to peptide | 2.44E − 13 | 36 | GO:0046777 | Protein autophosphorylation | 1.46E − 12 | 24 | GO:0072593 | Reactive oxygen species metabolic process | 5.02E − 12 | 26 | GO:0000302 | Response to reactive oxygen species | 9.15E − 12 | 24 |
| Molecular functions | GO:0004879 | Nuclear receptor activity | 2.07E − 24 | 21 | GO:0098531 | Transcription factor activity and direct ligand-regulated sequence-specific DNA binding | 2.07E − 24 | 21 | GO:0003707 | Steroid hormone receptor activity | 2.07E − 24 | 22 | GO:0004713 | Protein tyrosine kinase activity | 5.32E − 16 | 22 | GO:0033293 | Monocarboxylic acid binding | 2.94E − 10 | 13 | GO:0031406 | Carboxylic acid binding | 1.41E − 09 | 19 | GO:0043177 | Organic acid bindings | 1.47E − 09 | 19 | GO:0004714 | Transmembrane receptor protein tyrosine kinase activity | 1.45E − 07 | 10 | GO:0004715 | Nonmembrane spanning protein tyrosine kinase activity | 1.52E − 07 | 9 | GO:0004175 | Endopeptidase activity | 1.52E − 07 | 22 |
| Cellular components | GO:0031983 | Vesicle lumen | 8.41E − 08 | 23 | GO:0060205 | Cytoplasmic vesicle lumen | 1.35E − 07 | 22 | GO:0045121 | Membrane raft | 1.35E − 07 | 21 | GO:0098857 | Membrane microdomain | 1.35E − 07 | 21 | GO:0034774 | Secretory granule lumen | 1.69E − 07 | 21 | GO:0098589 | Membrane region | 1.69E − 07 | 21 | GO:0101002 | Ficolin-1-rich granule | 7.38E − 05 | 13 | GO:0031012 | Extracellular matrix | 2.70E − 04 | 20 | GO:1904813 | Ficolin-1-rich granule lumen | 2.70E − 04 | 10 | GO:0031256 | Leading edge membrane | 2.70E − 04 | 11 |
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