Research Article
Traditional Chinese Medicine Containing Arsenic Treated MDS Patients Effectively through Regulating Aberrant Hypomethylation
Table 1
Patients demographics and MDS disease characteristics.
| | Item | Case (%) |
| | Age | | | ≥60 years | 19 (14.07) | | <60 years | 116 (85.92) |
| | Male | 67 (49.62) |
| | Female | 68 (50.38) |
| | WHO subtypes | | | RCMD | 130 (96.29) | | RAEB-1 | 3 (2.22) | | RARB-2 | 2 (1.49) |
| | IPSS classification | | | Intermediate-1 risk | 8 (5.93) | | Intermediate-2 risk | 127 (94.07) |
| | Cytogenetic findings | | | Normal/diploid | 93 (68.88) | | +8 | 8 (5.92) | | Complex (≥3 abnormalities) | 5 (3.70) | | 20q- | 5 (3.70) | | -Y | 3 (2.25) | | Other | 21 (15.55) |
| | Cell-lineage cytopenia | | | Unilineage | 23 (17.04) | | Bilineage | 43 (31.85) | | Trilineage | 69 (51.11) |
| | Baseline cytopenia(s) | | | Anemia | 6 (4.44) | | Neutropenia | 3 (2.22) | | Thrombocytopenia | 14 (10.37) | | Anemia + neutropenia | 11 (8.15) | | Neutropenia + thrombocytopenia | 10 (7.41) | | Anemia + thrombocytopenia | 22 (16.30) | | Anemia + neutropenia + thrombocytopenia | 69 (51.11) |
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RCMD: Refractory cytopenia with multilineage dysplasia; RAEB-1: Refractory anemia with excess blasts-1; RAEB-2: Refractory anemia with excess blasts-2.
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