Research Article

Mogroside V Protects against Hepatic Steatosis in Mice on a High-Fat Diet and LO2 Cells Treated with Free Fatty Acids via AMPK Activation

Figure 3

Effect of MV on FFAs-induced lipid accumulation in LO2 cells. (a) Representative photomicrographs of Oil Red O staining of LO2 cells; (b) cell viability (n = 6); (c) cellular Oil Red O content was extracted from cells and quantified (n = 6); (d) TG content was measured by the corresponding assay kit (n = 8); (e) FASN protein expression; (f) SREBP-1 protein expression; (g) PPAR-γ protein expression; (h) PPAR-α protein expression; (i) CPT-1A protein expression. All protein expressions were measured by western blotting assay (n = 3-4). Data are presented as mean ± SEM. vs. control; vs. control; vs. control; vs. FFAs; vs. FFAs; vs. FFAs.
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