Mogroside V Protects against Hepatic Steatosis in Mice on a High-Fat Diet and LO2 Cells Treated with Free Fatty Acids via AMPK Activation

Figure 4

MV ameliorated lipid accumulation in liver tissues of HFD-fed mice and in FFAs-treated LO2 cells via AMPK. (a) Phospho-AMPK/AMPK protein expression in liver tissues (n = 4); (b) phospho-AMPK/AMPK protein expression in cells (n = 3); (c) Oil Red O staining of LO2 cells; (d) Oil Red O content quantification of LO2 cells (n = 6); (e) TG assay. All data are shown as mean ± SEM. CC: Compound c. vs. control; vs. HFD; vs. HFD; vs. FFAs; vs. FFAs; vs. FFAs + CC + 60 μM MV; vs. FFAs + CC + 60 μM MV.

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