Jie-Du-Hua-Yu Granules Promote Liver Regeneration in Rat Models of Acute Liver Failure: miRNA-mRNA Expression Analysis

Figure 5

JDHY granules enhance DNA replication. (a) Therapeutic mechanisms of the JDHY granules in enhancing DNA replication. (b) mRNA/miRNA expression of MCM3/miR-3549. (c) Western blot analysis of MCM3 and CDK4. β-actin was probed as loading control. (d) Expression of MCM3 and (e) CDK4. n = 10 in the control group; n = 7 in the model group; n = 10 in the JDHY group. Abbreviations: P, phosphorylation; A, activation; ↓, downregulation; ↑, upregulation; MCM3, minichromosome maintenance complex3; CDK4, cyclin-dependent kinase 4.

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