Xanthomicrol Exerts Antiangiogenic and Antitumor Effects in a Mouse Melanoma (B16F10) Allograft Model

Figure 7

Xanthomicrol decreased Akt phosphorylation in vivo. After 21 consecutive days of treatment, excised tumor tissues from B16F10 allografted animals in different groups were used for protein extraction and subsequent western blot analysis of Akt, phosphorylated Akt (a), Erk, and phosphorylated Erk (b). β-Actin was used as loading control. Data are represented as mean ± SEM (^∗ vs. vehicle-treated mice).

(a)

(b)