HPLC-MS/MS Analysis of <i>Aconiti Lateralis Radix Praeparata</i> and Its Combination with Red Ginseng Effect on Rat CYP450 Activities Using the Cocktail Approach

<div>Representative MRM chromatograms of probe drugs and IS in rat plasma samples. (a) Blank plasma sample; (b) plasma sample from a rat after an intravenous administration; (c) blank plasma sample spiked with probe drugs and IS. 1. 7-Hydroxycoumarin; 2. omeprazole; 3. dextromethorphan; 4. bupropion; 5. phenacetin; 6. dapsone; 7. tolbutamide; 8. amodiaquine; and 9. diazepam (IS).</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 1: HPLC-MS/MS Analysis of <i>Aconiti Lateralis Radix Praeparata</i> and Its Combination with Red Ginseng Effect on Rat CYP450 Activities Using the Cocktail Approach 

Figure 1 | HPLC-MS/MS Analysis of Aconiti Lateralis Radix Praeparata and Its Combination with Red Ginseng Effect on Rat CYP450 Activities Using the Cocktail Approach 