In Vivo Antiplasmodial Activity of Different Solvent Extracts of Myrianthus libericus Stem Bark and Its Constituents in Plasmodium berghei-Infected Mice

Table 2

Parasitaemia level, % suppression, and survival time of the P. berghei-infected mice treated with MLB and solvent fractions in the suppressive test.

Sample	Dose (mg·kg^−1)	% parasitaemia	% suppression	Mean survival time (days)
NC	10 mL·kg^−1	67.58 ± 1.31	—	7.00 ± 0.89
MLB	50	32.26 ± 0.57^b4	52.26	9.83 ± 0.30^b4
MLB	100	24.18 ± 0.54^b4	65.40	14.50 ± 0.43^b4
MLB	200	15.47 ± 1.05^b4	77.11	24.00 ± 0.58^b4
MLB-Pet	200	60.05 ± 0.90^b1	5.62	7.94 ± 0.48
MLB-EtOAc	200	16.80 ± 0.92^b4	73.59	23.81 ± 0.72^b4
MLB-MeOH	200	27.93 ± 0.60^b4	56.11	13.94 ± 0.67^b4
ART	2	0.75 ± 0.02^b4	98.89	30.00 ± 0.00^b4

Values are presented as mean ± SEM, n = 6. NC = vehicle-treated group; ART = artesunate. Values are significantly different at and , ^bcompared to the vehicle-treated group.