In Vivo Antiplasmodial Activity of Different Solvent Extracts of Myrianthus libericus Stem Bark and Its Constituents in Plasmodium berghei-Infected Mice

Table 3

Effect of MLB on body weight and packed cell volume in the four-day suppressive test.

Dose (mg·kg^−1)	Body weight (g)			Packed cell volume
	Day 0	Day 4	W	Day 0	Day 4	PCV
NC	23.40 ± 0.81	18.59 ± 0.31^a1	−4.81	50.90 ± 1.08	45.77 ± 0.66^a3	−5.13
50	20.95 ± 1.10	20.52 ± 1.21	−0.43	49.95 ± 0.81	47.15 ± 0.23	−2.8
100	21.08 ± 0.67	22.57 ± 0.92	1.49	51.22 ± 1.42	49.82 ± 0.27	−1.4
200	21.32 ± 0.65	22.20 ± 0.74	0.88	50.22 ± 0.97	49.42 ± 0.33	−0.8
ART (2)	20.95 ± 1.64	19.40 ± 2.02	−1.55	49.63 ± 0.89	48.80 ± 0.47	−0.83

Values are presented as mean ± SEM, n = 6. NC = vehicle-treated group; ART = artesunate. Values are significantly different at and , ^acompared to day 0.