In Vivo Antiplasmodial Activity of Different Solvent Extracts of Myrianthus libericus Stem Bark and Its Constituents in Plasmodium berghei-Infected Mice

Table 4

Parasitaemia level, % suppression, and mean survival time of P. berghei-infected mice in the curative test.

Dose (mg·kg^−1)	% parasitaemia		% suppression	Mean survival time (days)
	Day 3	Day 7
NC	43.70 ± 1.79	70.80 ± 2.01^a4	—	6.00 ± 0.93
50	46.35 ± 3.48	35.20 ± 0.61^a4,b4	50.28	11.33 ± 0.99^b4
100	47.19 ± 3.10	28.63 ± 1.90^a4,b4	59.56	13.67 ± 0.49^b4
200	39.71 ± 1.82	19.47 ± 1.13^a4,b4	72.50	21.50 ± 0.43^b4
ART (2)	40.06 ± 2.13	1.26 ± 0.10^a4,b4	98.22	29.67 ± 0.33^b4

Values are presented as mean ± SEM, n = 6. NC = vehicle-treated group; ART = artesunate. ⁴Values are significantly different at , ^acompared to day 3, ^bcompared to negative control.