In Vivo Antiplasmodial Activity of Different Solvent Extracts of Myrianthus libericus Stem Bark and Its Constituents in Plasmodium berghei-Infected Mice

Table 5

Effect of MLB on body weight and PCV in the curative test.

Dose (mg·kg^−1)	Body weight (g)			Packed cell volume
	Day 3	Day 7	W	Day 3	Day 7	PCV
NC	21.18 ± 0.52	18.06 ± 0.41^a1	−3.12	44.67 ± 0.62	41.95 ± 0.37^a4	−2.72
50	19.94 ± 1.06	20.32 ± 0.66	0.38	45.43 ± 0.52	43.82 ± 0.62^a1	−1.61
100	20.68 ± 0.70	21.99 ± 0.84	1.31	48.28 ± 0.21	47.05 ± 0.15	−1.23
200	20.93 ± 0.51	23.79 ± 0.71^a1	2.86	47.92 ± 0.45	47.28 ± 0.24	−0.64
ART (2)	21.83 ± 0.93	21.22 ± 0.69	−0.61	47.17 ± 0.31	46.95 ± 0.24	−0.22

Values are presented as mean ± SEM, n = 6. NC = vehicle-treated group; ART = Artesunate. Values are significantly different at ¹p < 0.05 and ⁴p < 0.0001, ^acompared to day 3.