In Vivo Antiplasmodial Activity of Different Solvent Extracts of Myrianthus libericus Stem Bark and Its Constituents in Plasmodium berghei-Infected Mice

Table 6

Parasitaemia level, % suppression, and mean survival time of P. berghei-infected mice treated with ML1 and ML2 in the suppressive test.

Dose (mg·kg^−1)		% parasitaemia	% suppression	Mean survival time (days)
NC	10 mL·kg^−1	65.12 ± 2.056	—	9.50 ± 0.76
ML1	10	33.24 ± 0.71^b4	48.95	11.67 ± 0.67^b1
	20	25.33 ± 0.65^b4	61.11	13.33 ± 0.56^b4
	30	18.05 ± 1.50^b4	72.28	22.17 ± 0.48^b4
ML2	10	33.49 ± 0.49^b4	48.57	10.67 ± 0.49
	20	26.21 ± 0.98^b4	59.75	12.17 ± 0.60^b2
	30	22.72 ± 1.21^b4	65.11	20.50 ± 0.43^b4
ART	2	0.00 ± 0.00^b4	100.00	30.00 ± 0.00^b4

Values are presented as mean ± SEM, n = 6. NC = vehicle-treated group; ART = artesunate. Values are significantly different at , , and , ^bcompared to the vehicle-treated group.