In Vivo Antiplasmodial Activity of Different Solvent Extracts of Myrianthus libericus Stem Bark and Its Constituents in Plasmodium berghei-Infected Mice
Table 9
Effect of ML1 and ML2 on body weight and PCV in the curative test.
Dose (mg kg−1)
Body weight (g)
Packed cell volume
Day 3
Day 7
W
Day 3
Day 7
PCV
NC
21.18 ± 0.52
18.06 ± 0.41a2
−3.12
44.67 ± 0.62
41.95 ± 0.37a2
−2.72
ML1
10
20.08 ± 0.43
18.16 ± 0.25
−1.92
45.40 ± 0.53
43.91 ± 0.57
−1.49
20
20.52 ± 0.63
19.27 ± 0.42
−1.25
47.00 ± 0.48
45.64 ± 0.44
−1.36
30
22.16 ± 0.72
21.37 ± 0.56
−0.79
47.77 ± 0.60
47.12 ± 0.27
−0.65
ML2
10
21.66 ± 0.71
18.86 ± 0.40a2
−2.8
46.56 ± 0.40
44.60 ± 0.62
−1.96
20
22.32 ± 0.76
20.64 ± 0.46
−1.68
48.45 ± 0.71
46.88 ± 0.61
−1.57
30
22.93 ± 0.67
21.59 ± 0.30
−1.34
49.08 ± 1.15
48.63 ± 0.25
−0.45
ART
2
21.83 ± 0.93
21.22 ± 0.69
−0.61
47.17 ± 0.31
46.95 ± 0.24
−0.22
Values are presented as mean ± SEM, n = 6. NC: vehicle-treated group; ART: artesunate. Values are significantly different at ,acompared to day 3.
