Research Article

A Phase II Pilot Trial to Evaluate CoBaT-Y017 Safety and Efficacy against Uncomplicated Falciparum Malaria versus Artemether-Lumefantrine in Benin Subjects

Table 3

Variation of mean of AST and ALT values of patients at different follow-up days in the study arms.

ParametersTreatment armsD1 (baseline)D4D7D14D21D28

ASTCoBaT-Y01725.66±18.2928.41 ± 15.4628.20 ± 17.2622.96 ± 14.8919.07 ± 5.4020.81 ± 7.95
AL19.06±11.8919.09 ± 6.6015.85 ± 5.7822.26 ± 9.5019.72 ± 9.5315.88 ± 4.17

ALTCoBaT-Y01726.94±18.8929.91 ± 17.2234.25 ± 23.1622.79 ± 9.3024.64 ± 18.9821.21 ± 10.61
AL21.12±13.8319.85 ± 10.0619.15 ± 6.7222.69 ± 14.6321.06 ± 12.8519.49 ± 10.17

Values were expressed as mean ± SD.