A Phase II Pilot Trial to Evaluate CoBaT-Y017 Safety and Efficacy against Uncomplicated Falciparum Malaria versus Artemether-Lumefantrine in Benin Subjects

Table 4

Variation of mean values of creatinine and urea at different follow-up days in the study arms.

Parameters	Treatment arms	D1 (baseline)	D4	D7	D14	D21	D28
Creatinine	CoBaT-Y017	11.50 ± 1.85	17.73 ± 22.33	10.86 ± 1.80	11.40 ± 2.73	10.43 ± 1.39	11.08 ± 11.68
	AL	10.51 ± 3.7	10.83 ± 3.52	12.37 ± 5.05	10.33 ± 1.71	10.46 ± 1.49	10.30 ± 1.77
Urea	CoBaT-Y017	0.14 ± 0.05	0.19 ± 0.21	0.15 ± 0.36	0.15 ± 0.07	0.15 ± 0.05	0.12 ± 0.03
	AL	0.15 ± 0.06	0.14 ± 0.04	0.18 ± 0.14	0.13 ± 0.03	0.15 ± 0.06	0.20 ± 0.20

Values are expressed as mean ± SD.