So-Ochim-Tang-Gamibang, a Traditional Herbal Formula, Ameliorates Depression by Regulating Hyperactive Glucocorticoid Signaling In Vitro and In Vivo

Figure 2

Effects of SOCG on depressive-like behavior in WKY rats. The animals were subjected to chronic restraint stress for 2 weeks, and SOCG was orally administered (300 mg/kg). (a) Travelled distance in the OFT, (b) immobility duration in the FST, and (c) sucrose preference in the SPT were measured. The data are presented as the mean ± SEM. ##, significant difference compared to the naive group. , , and , significant difference compared to the control group. AMI: amitriptyline (10 mg/kg).

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