Research Article
The Role of Oxymatrine in Amelioration of Acute Lung Injury Subjected to Myocardial I/R by Inhibiting Endoplasmic Reticulum Stress in Diabetic Rats
Figure 3
OMT ameliorates myocardial I/R-induced acute lung injury in diabetic rats. (a), (b), and (c) Expression levels of inflammatory factors IL-6, TNF-α, and IL-17. (d) Severity of lung injury expressed as the injury score. (e) Histopathological changes in rat lung tissues from control and diabetic rats subjected to sham or myocardial I/R surgery (original magnification, x200). All values are expressed as the mean ± SD, n = 8. vs. the Sham group; vs. the I/R group; vs. the DM + I/R group. OMT, oxymatrine; I/R, ischemia/reperfusion; IL, interleukin; TNF-α, tumor necrosis factor-α; DM, diabetes mellitus.
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