Research Article

The Role of Oxymatrine in Amelioration of Acute Lung Injury Subjected to Myocardial I/R by Inhibiting Endoplasmic Reticulum Stress in Diabetic Rats

Figure 4

Effects of OMT on endoplasmic reticulum stress during myocardial I/R-induced acute lung injury in diabetic rats. mRNA expression levels of (a) GRP78 and (b) CHOP were detected using Western blot analysis. Protein expression levels of (c) GRP78 and (d) CHOP were determined using reverse transcription-quantitative PCR. Values are expressed as the mean ± SD from three independent experiments, n = 3. and vs. the Sham group; vs. the I/R group; , vs. the DM + I/R group. OMT, oxymatrine; I/R, ischemia/reperfusion; GRP78, endoplasmic reticulum chaperone BiP; CHOP, DNA damage-inducible transcript 3 protein; DM, diabetes mellitus.
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