Research Article
Amelioration of Rheumatoid Arthritis by Anacardium occidentale via Inhibition of Collagenase and Lysosomal Enzymes
Table 1
Treatment with A. occidentale nearly normalized all the hematological parameters.
| Parameters | Groups | Control | Arthritic | AO (100 mg/kg) | AO (200 mg/kg) | Piroxicam |
| TLC (103) | 7.305 ± 0.388 | 9.293 ± 0.569 | 8.017 ± 0.321 | 8.017 ± 0.321 | 7.807 ± 0.663 | Neutrophil (%) | 52.66 ± 3.369 | 66.78 ± 2.660 | 60.43 ± 3.972 | 57.94 ± 3.052 | 54.50 ± 3.355 | Lymphocytes (%) | 31.18 ± 0.608 | 33.66 ± 0.708 | 33.27 ± 1.693 | 32.02 ± 0.551 | 31.96 ± 0.532 | Monocytes (%) | 1.610 ± 0.133 | 2.412 ± 0.200 | 2.303 ± 0.1720 | 2.088 ± 0.117 | 2.032 ± 0.146 | Basophils (%) | 0.8050 ± 0.034 | 0.8500 ± 0.052 | 0.8400 ± 0.030 | 0.8267 ± 0.043 | 0.8117 ± 0.0256 | Platelet count (103) | 4.350 ± 0.250 | 5.567 ± 0.325 | 5.133 ± 0.189 | 4.908 ± 0.364 | 4.882 ± 0.184 | RBC (106) | 5.827 ± 0.325 | 4.163 ± 0.405 | 4.450 ± 0.424 | 5.057 ± 0.364 | 4.963 ± 0.144 | Hb (g/dL) | 14.66 ± 0.3985 | 11.67 ± 0.8179 | 12.79 ± 0.3164 | 13.36 ± 0.4298 | 13.02 ± 0.6174 |
|
|
indicating significant difference compared to control group, , , and indicating significant difference compared to arthritic group. |