Research Article

Amelioration of Rheumatoid Arthritis by Anacardium occidentale via Inhibition of Collagenase and Lysosomal Enzymes

Table 1

Treatment with A. occidentale nearly normalized all the hematological parameters.

ParametersGroups
ControlArthriticAO (100 mg/kg)AO (200 mg/kg)Piroxicam

TLC (103)7.305 ± 0.3889.293 ± 0.5698.017 ± 0.3218.017 ± 0.3217.807 ± 0.663
Neutrophil (%)52.66 ± 3.36966.78 ± 2.66060.43 ± 3.97257.94 ± 3.05254.50 ± 3.355
Lymphocytes (%)31.18 ± 0.60833.66 ± 0.70833.27 ± 1.69332.02 ± 0.55131.96 ± 0.532
Monocytes (%)1.610 ± 0.1332.412 ± 0.2002.303 ± 0.17202.088 ± 0.1172.032 ± 0.146
Basophils (%)0.8050 ± 0.0340.8500 ± 0.0520.8400 ± 0.0300.8267 ± 0.0430.8117 ± 0.0256
Platelet count (103)4.350 ± 0.2505.567 ± 0.3255.133 ± 0.1894.908 ± 0.3644.882 ± 0.184
RBC (106)5.827 ± 0.3254.163 ± 0.4054.450 ± 0.4245.057 ± 0.3644.963 ± 0.144
Hb (g/dL)14.66 ± 0.398511.67 ± 0.817912.79 ± 0.316413.36 ± 0.429813.02 ± 0.6174

indicating significant difference compared to control group, , , and indicating significant difference compared to arthritic group.