Arenobufagin Promoted Oxidative Stress-Associated Mitochondrial Pathway Apoptosis in A549 Non-Small-Cell Lung Cancer Cell Line

Figure 4

Effect of ARE on the expression of apoptosis-related genes in A549 cells. A549 cells were treated with ARE (10–40 nM) for 24 h. The mRNA levels of Bcl-2, Bax, caspase-9, and caspase-3 were measured by real-time PCR (Figures 4(a)–4(d)). The results are expressed as mean ± SD (n = 3). versus the control group.

(a)

(b)

(c)

(d)