Plastrum Testudinis Extracts Promote NSC Differentiation into Dopaminergic Neuron by Regulating the Interaction of TET1 and FoxA2

Figure 1

Effects of PT on substantia nigra (SN) of midbrain for PD rats (400x). (a) Staining of TH in rat brain (SN) tissue sections by IHC analysis (magnification: 400x). (b) Statistical analysis of the positive rate of TH-positive cells by using ImageJ software. (c) Staining of 5hmC in rat brain (SN) tissue sections by IHC analysis (magnification: 400x). (d) Statistical analysis of the positive rate of 5hmC-positive cells by using ImageJ software. (e) Staining of TET1 in rat brain (SN) tissue sections by IHC analysis (magnification: 400x). (f) Statistical analysis of the positive rate of TET1-positive cells by using ImageJ software. The positive cells were stained brown, marked by red arrow (↑). compared with blank control; compared with PD model. ns: not significant; : values. The description of the statistical analyses is provided in Supplementary Table S1.