Suppression of Dynamical Network Biomarker Signals at the Predisease State (Mibyou) before Metabolic Syndrome in Mice by a Traditional Japanese Medicine (Kampo Formula) Bofutsushosan

Figure 2

Effects of BTS on TSOD mice. (a) Box plots of body weights and blood sugar concentrations at 7 weeks of age. In the left most box, the median line matched the box bottom. values were based on the two-tailed Welch’s t-test. (b) Venn diagram of four DEG sets. (c) Heatmap of the union set of the four DEG sets. The color scale shows the z-score (per row) of the log expression. (d) GO annotations enriched in the largest cluster. A KEGG pathway “Olfactory transduction” was also enriched in the cluster (59 genes overlapping).

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