Network Pharmacology-Based Approach to Investigate the Mechanisms of Mahai Capsules in the Treatment of Cardiovascular Diseases

Table 1

The candidate compounds and putative target proteins of MHC.

Code	Molecule name	MW	OB (%)	DL
M1	Mairin	456.78	55.38	0.78
M2	Jaranol	314.31	50.83	0.29
M3	Hederagenin	414.79	36.91	0.75
M4	(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-[(2R,5S)-5-propan-2-yloctan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol	428.82	36.23	0.78
M5	Isorhamnetin	316.28	49.6	0.31
M6	3,9-Di-O-methylnissolin	314.36	53.74	0.48
M7	5′-Hydroxyiso-muronulatol-2′,5′-di-O-glucoside	642.67	41.72	0.69
M8	7-O-Methylisomucronulatol	316.38	74.69	0.3
M9	9,10-Dimethoxypterocarpan-3-O-β-D-glucoside	462.49	36.74	0.92
M10	(6aR,11aR)-9,10-Dimethoxy-6a,11a-dihydro-6H-benzofurano[3,2-c]chromen-3-ol	300.33	64.26	0.42
M11	Bifendate	418.38	31.1	0.67
M12	Formononetin	268.28	69.67	0.21
M13	Isoflavanone	316.33	109.99	0.3
M14	Calycosin	284.28	47.75	0.24
M15	Kaempferol	286.25	41.88	0.24
M16	FA	441.45	68.96	0.71
M17	(3R)-3-(2-Hydroxy-3,4-dimethoxyphenyl)chroman-7-ol	302.35	67.67	0.26
M18	Isomucronulatol-7,2′-di-O-glucosiole	626.67	49.28	0.62
M19	1,7-Dihydroxy-3,9-dimethoxy pterocarpene	314.31	39.05	0.48
M20	Quercetin	302.25	46.43	0.28
M21	(2R)-5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one	272.27	42.36	0.21
M22	(S)-stylopine	323.37	51.15	0.85
M23	Ziziphin_qt	472.78	66.95	0.62
M24	Icaride A	404.5	48.74	0.43
M25	Isostrychnine N-oxide (I)	352.47	35.45	0.8
M26	Isostrychnine N-oxide (II)	350.45	37.33	0.8
M27	Lokundjoside_qt	406.57	32.82	0.76
M28	Vomicine	408.54	47.56	0.65
M29	Brucine-N-oxide	410.51	49.17	0.38
M30	Isobrucine	334.45	33.58	0.8
M31	Brucine N-oxide	410.51	52.63	0.38
M32	Stigmasterol	412.77	43.83	0.76
M33	(+)-Catechin	290.29	54.83	0.24
M34	Beta-sitosterol	414.79	36.91	0.75
M35	Stigmasterol	412.77	43.83	0.76
M36	(2R,3R,3aS)-3a-Allyl-2-(1,3-benzodioxol-5-yl)-5-methoxy-3-methyl-2,3-dihydrobenzofuran-6-one	340.4	59.99	0.43
M37	Denudatin B	356.45	61.47	0.38
M38	Futokadsurin C	356.45	61.09	0.45
M39	Galgravin	372.5	57.12	0.39
M40	(2S,3S,4S,5S)-2,5-Bis(3,4-dimethoxyphenyl)-3,4-dimethyltetrahydrofuran	372.5	57.12	0.39
M41	Hancinone	340.4	39.31	0.44
M42	Isofutoquinol A	354.43	59.2	0.48
M43	(1R,5S,6R,7R,8R)-3-Allyl-6-(3,4-dimethoxyphenyl)-8-hydroxy-1-methoxy-7-methyl-4-bicyclo[3.2.1]oct-2-enone	358.47	64.65	0.35
M44	Bicyclo(3.2.1)oct-3-ene-2,8-dione, 7-(4-hydroxy-3-methoxyphenyl)-5-methoxy-6-methyl-3-(2-propenyl)-, (1R-(6-endo,7-exo))-	342.42	94.67	0.32
M45	Acetic acid [(1R,5S,6R,7R,8R)-3-allyl-6-(3,4-dimethoxyphenyl)-1-methoxy-7-methyl-4-oxo-8-bicyclo[3.2.1]oct-2-enyl] ester	400.51	59.93	0.46
M46	(2S,3S)-2-(3,4-Dimethoxyphenyl)-7-methoxy-3-methyl-2,3-dihydrobenzofuran-5-carbaldehyde	328.39	42.15	0.32
M47	Kadsurenone	356.45	54.72	0.38
M48	Kadsurin A	372.45	56.83	0.5
M49	Kadsurin B	358.47	30.55	0.46
M50	(4R)-2-Allyl-4-[(E)-2-(4-hydroxy-3-methoxyphenyl)-1-methylvinyl]-4,5-dimethoxy-1-cyclohexa-2,5-dienone	356.45	55.14	0.3
M51	Piperkadsin B	430.54	55.44	0.41
M52	Piperlactam S	295.31	40.44	0.4
M53	Stigmasterol	412.77	43.83	0.76
M54	N-Coumaroyltyramine	283.35	85.63	0.2
M55	Wallichinine	370.48	61.64	0.33
M56	Futoquinol	354.43	59.83	0.36
M57	Beta-sitosterol	414.79	36.91	0.75
M58	Acetylbullatantriol	298.47	40.21	0.18
M59	Maristeminol	322.54	30.64	0.38
M60	Eupatin	360.34	50.8	0.41
M61	Mutatochrome	552.96	48.64	0.61
M62	Physciondiglucoside	608.6	41.65	0.63
M63	Procyanidin B-5,3′-O-gallate	730.67	31.99	0.32
M64	Rhein	284.23	47.07	0.28
M65	Sennoside E_qt	524.5	50.69	0.61
M66	Torachrysone-8-O-beta-D-(6′-oxayl)-glucoside	480.46	43.02	0.74
M67	Toralactone	272.27	46.46	0.24
M68	Emodin-1-O-beta-D-glucopyranoside	432.41	44.81	0.8
M69	Sennoside D_qt	524.5	61.06	0.61
M70	Daucosterol_qt	386.73	35.89	0.7
M71	Palmidin A	510.52	32.45	0.65
M72	Beta-sitosterol	414.79	36.91	0.75
M73	Aloe-emodin	270.25	83.38	0.24
M74	Gallic acid-3-O-(6′-O-galloyl)-glucoside	484.4	30.25	0.67
M75	(-)-Catechin	290.29	49.68	0.24