Effect of <i>Coptis chinensis</i> on Biofilm Formation and Antibiotic Susceptibility in <i>Mycobacterium abscessus</i>

<div>Susceptibility of <i>M. abscessus</i> to <i>C. chinensis</i> or berberine-HCl. The CFU formed of <i>M. abscessus</i> in 7H9 medium alone (the control group) and after treatment with the indicated concentrations of <i>C. chinensis</i> or berberine-HCl were counted by plating. Survival CFU and the relative percentage were expressed. As determined by the Mann–Whitney Rank Sum Test, statistically significant reductions (asterisk) in relative percentage of survival CFU of <i>M. abscessus</i> were observed for 1/4 × MIC, 1/2 × MIC, MIC, 2 × MIC, and 4 × MIC following the addition of <i>Coptis chinensis</i> (a) and 1/4 × MIC, 1/2 × MIC, MIC, and 2 × MIC following the addition of berberine-HCl (b). CFU: colony forming unit. CTL: control. MIC: minimal inhibitory cncentration. 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Evidence-Based Complementary and Alternative Medicine

fig1

Figure 1

Figure 1: Effect of <i>Coptis chinensis</i> on Biofilm Formation and Antibiotic Susceptibility in <i>Mycobacterium abscessus</i> 

Evidence-Based Complementary and Alternative Medicine

Effect of Coptis chinensis on Biofilm Formation and Antibiotic Susceptibility in Mycobacterium abscessus

Figure 1