Research Article
Analysis of the Molecular Mechanisms of the Effects of Prunella vulgaris against Subacute Thyroiditis Based on Network Pharmacology
Table 2
The topological parameters of hub targets.
| Number | Node | Degree centrality (DC) | Betweenness centrality (BC) |
| 1 | TP53 | 33 | 0.146655 | 2 | IL6 | 32 | 0.103348 | 3 | JUN | 30 | 0.076404 | 4 | MAPK1 | 30 | 0.062201 | 5 | MAPK8 | 29 | 0.089256 | 6 | TNF | 28 | 0.057882 | 7 | VEGFA | 27 | 0.065223 | 8 | EGF | 23 | 0.053058 | 9 | IL-1β | 22 | 0.009747 | 10 | PTGS2 | 22 | 0.044508 | 11 | APP | 21 | 0.191657 | 12 | EGFR | 20 | 0.021937 | 13 | ESR1 | 19 | 0.028738 | 14 | CCL2 | 19 | 0.013005 | 15 | MAPK14 | 17 | 0.004943 | 16 | AR | 17 | 0.026691 | 17 | HMOX1 | 16 | 0.01145 | 18 | NOS3 | 15 | 0.003683 |
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