Research Article
HPLC-MS and Network Pharmacology Analysis to Reveal Quality Markers of Huo-Xue-Jiang-Tang Yin, a Chinese Herbal Medicine for Type 2 Diabetes Mellitus
Table 2
Result of pathway enrichment (top 20).
| | ID | Description | value | Target gene count |
| | hsa04151 | PI3K-Akt signaling pathway | 3.19 × 10−6 | 17 | | hsa04010 | MAPK signaling pathway | 1.12 × 10−6 | 16 | | hsa04933 | AGE-RAGE signaling pathway | 1.04 × 10−11 | 15 | | hsa04015 | Rap1 signaling pathway | 1.06 × 10−5 | 13 | | hsa04915 | Estrogen signaling pathway | 6.86 × 10−7 | 12 | | hsa04014 | Ras signaling pathway | 1.36 × 10−4 | 12 | | hsa04625 | C-type lectin receptor signaling pathway | 2.84 × 10−7 | 11 | | hsa04066 | HIF-1 signaling pathway | 4.59 × 10−7 | 10 | | hsa04926 | Relaxin signaling pathway | 2.49 × 10−6 | 11 | | hsa04068 | FoxO signaling pathway | 2.90 × 10−6 | 11 | | hsa04022 | cGMP-PKG signaling pathway | 2.97 × 10−6 | 10 | | hsa04668 | TNF signaling pathway | 4.83 × 10−6 | 10 | | hsa04152 | AMPK signaling pathway | 8.98 × 10−6 | 10 | | hsa04910 | Insulin signaling pathway | 2.88 × 10−5 | 10 | | hsa04072 | Phospholipase D signaling pathway | 5.60 × 10−5 | 10 | | hsa04150 | mTOR signaling pathway | 7.42 × 10−5 | 10 | | hsa04920 | Adipocytokine signaling pathway | 6.00 × 10−7 | 9 | | hsa04211 | Longevity regulating pathway | 5.27 × 10−6 | 9 | | hsa04657 | IL-17 signaling pathway | 8.30 × 10−6 | 9 | | hsa04620 | Toll-like receptor signaling pathway | 1.90 × 10−5 | 9 |
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