Evidence-Based Complementary and Alternative Medicine

Research Article

Chinese Patent Medicine as Adjuvant for Mild-to-Moderate Active Ulcerative Colitis: A Network Meta-Analysis of Randomized Controlled Trials

Table 5

Adverse events, recurrence rate, disappearance of mucopurulent bloody stool/abdominal pain/diarrhea/tenesmus, and Mayo score based on network meta-analysis.
(a) Adverse events
XLSplusM            
0.00 (0.00, 0.02)FZLZplusM           
0.00 (0.00, 0.02)0.84 (0.04, 20.86)XLS          
0.00 (0.00, 0.10)5.53 (0.33, 133.79)6.67 (0.31, 213.75)BPYCplusM         
0.00 (0.00, 0.02)1.31 (0.07, 22.05)1.48 (0.06, 33.09)0.23 (0.01, 3.90)ZKplusM        
0.00 (0.00, 0.02)1.37 (0.13, 15.57)1.59 (0.11, 25.97)0.26 (0.02, 2.64)1.08 (0.09, 12.93)CYNplusM       
0.00 (0.00, 0.02)1.42 (0.19, 11.04)1.63 (0.16, 21.02)0.26 (0.02, 1.84)1.12 (0.15, 9.04)1.03 (0.28, 4.01)M      
0.00 (0.00, 0.03)1.78 (0.13, 26.89)2.00 (0.11, 43.38)0.32 (0.02, 4.61)1.36 (0.10, 21.44)1.32 (0.14, 12.25)1.24 (0.21, 7.51)SMIplusM     
0.00 (0.00, 0.02)1.11 (0.13, 9.98)1.35 (0.11, 18.09)0.21 (0.02, 1.73)0.91 (0.10, 8.17)0.84 (0.18, 3.88)0.80 (0.35, 1.79)0.65 (0.09, 4.39)KFXplusM    
0.00 (0.00, 0.01)0.89 (0.07, 11.73)1.00 (0.06, 19.30)0.16 (0.01, 2.02)0.66 (0.05, 9.93)0.63 (0.08, 5.21)0.62 (0.12, 3.13)0.48 (0.04, 5.38)0.77 (0.12, 4.85)FFHBplusM   
0.00 (0.00, 0.07)3.59 (0.17, 76.39)3.98 (0.17, 125.54)0.64 (0.02, 13.17)2.69 (0.14, 65.55)2.60 (0.20, 38.32)2.48 (0.27, 26.88)2.04 (0.12, 36.46)3.05 (0.30, 38.01)4.18 (0.26, 71.82)YNBYplusM  
0.00 (0.00, 0.02)1.26 (0.13, 14.65)1.52 (0.11, 24.46)0.24 (0.02, 2.44)1.03 (0.10, 11.71)0.95 (0.16, 5.77)0.92 (0.27, 3.16)0.73 (0.09, 6.22)1.12 (0.27, 5.01)1.49 (0.20, 11.78)0.38 (0.03, 4.50)DSIplusM 
0.00 (0.00, 0.01)0.78 (0.06, 11.28)0.90 (0.05, 17.74)0.14 (0.01, 1.94)0.61 (0.05, 9.39)0.57 (0.07, 5.10)0.56 (0.10, 3.07)0.44 (0.04, 5.17)0.68 (0.11, 4.74)0.92 (0.09, 9.72)0.22 (0.01, 3.68)0.60 (0.07, 4.93)DSFplusM
(b) Recurrence rate
DSFplusM            
0.28 (0.02, 4.13)DSIplusM           
0.26 (0.02, 3.25)0.87 (0.07, 11.72)GCZXplusM          
0.59 (0.08, 5.26)1.96 (0.26, 19.28)2.23 (0.33, 20.99)KFXplusM         
0.13 (0.02, 0.78)0.45 (0.07, 3.03)0.51 (0.09, 3.32)0.24 (0.07, 0.57)M        
0.58 (0.03, 16.00)2.07 (0.11, 62.18)2.17 (0.12, 50.57)1.05 (0.08, 14.13)4.61 (0.44, 56.19)XLSplusM       
(c) Disappearance of mucopurulent bloody stool
YNBYplusM            
2.10 (0.32, 16.03)M           
0.79 (0.05, 13.00)0.38 (0.05, 2.82)ZKplusM          
0.45 (0.02, 8.86)0.22 (0.02, 1.85)0.57 (0.03, 11.39)XLSplusM         
1.91 (0.12, 34.79)0.90 (0.12, 7.23)2.43 (0.14, 44.25)4.36 (0.22, 90.77)XLS        
(d) Disappearance of abdominal pain
M            
0.30 (0.03, 3.05)ZKplusM           
0.16 (0.01, 1.86)0.51 (0.01, 16.91)XLSplusM          
0.40 (0.04, 4.63)1.37 (0.05, 36.72)2.68 (0.08, 97.04)XLSplusM         
(e) Disappearance of diarrhea
KFXplusM            
7.40 (0.52, 117.45)M           
2.21 (0.07, 83.33)0.31 (0.03, 3.26)ZKplusM          
1.85 (0.05, 76.22)0.26 (0.02, 2.94)0.85 (0.02, 22.98)XLSplusM         
6.31 (0.18, 268.20)0.85 (0.08, 9.65)2.75 (0.10, 79.92)3.30 (0.11, 114.24)XLS        
(f) Disappearance of tenesmus
ZKplusM            
0.47 (0.01, 27.37)M           
0.00 (0.00, 0.02)0.00 (0.00, 0.02)KFXplusM          
(g) Mayo score
DSIplusM            
−1.36 (−4.42, 1.75)JCNplusM           
−1.59 (−3.73, 0.54)−0.22 (−2.46, 2.00)M          
Significant results are in bold.