Research Article

Liu Wei Di Huang Wan and the Delay of Insulin Use in Patients with Type 2 Diabetes in Taiwan: A Nationwide Study

Table 3

Demographic characteristics of subjects with diabetes from National Health Insurance Research Database of Taiwan, 2000–2012.

CharacteristicsInsulin users (%)Insulin nonusers (%)

Total diabetic patients17,45152,585
Sex
 Male8,538 (48.9)25,559 (48.6)
 Female8,913 (51.1)27,026 (51.4)

Age (years)
 Mean ± SD55.4 ± 13.852.7 ± 13.2
 <506,093 (34.9)22,672 (43.1)
 50–646,284 (36.0)18,986 (36.1)
 ≥655,074 (29.1)10,927 (20.8)

Comorbidity
 Hypertension4,372 (25.1)11,866 (22.6)
 Hyperlipidemia2,634 (15.1)10,062 (19.1)
 Coronary artery disease2,984 (17.1)8,242 (15.7)
 Heart failure1,115 (6.4)2,560 (4.9)
 Stroke3,011 (17.3)7,573 (14.4)
 Chronic kidney disease914 (5.2)2,615 (5.0)

Antidiabetics
 Biguanides14,000 (80.2)41,764 (79.4)
 Sulfonylureas14,572 (83.5)37,808 (71.9)
 Combinations1,991 (11.4)9,901 (18.8)
 Alpha-glucosidase inhibitors5,410 (31.0)12,156 (23.1)
 Thiazolidinediones5,618 (32.2)11,239 (21.4)
 DPP-4 inhibitors1,619 (9.3)9,207 (17.5)
 Others4,074 (23.3)8,285 (15.8)

Complexity of antidiabetics
 None2,069 (11.9)6,111 (11.6)
 1 drug1,332 (7.6)8,261 (15.7)
 2 drugs4,905 (28.1)14,972 (28.5)
 3 drugs and above9,145 (52.4)23,241 (44.2)

Herbal product usage (days)
 Never used9,414 (53.9)22,715 (43.2)
 CHPs without LWDHW4,486 (25.7)16,476 (31.3)
 LWDHW3,551 (20.3)13,394 (25.5)