Research Article

Liu Wei Di Huang Wan and the Delay of Insulin Use in Patients with Type 2 Diabetes in Taiwan: A Nationwide Study

Table 4

Hazard of insulin use of TCM including LWDHW estimated using cox proportional hazards model with National Health Insurance Research Database in Taiwan, 2000–2012.

Herbal product usageCase/populationaHR (95% CI)aHR (95% CI)

Total diabetic patients17,451/70,036
 Never used9,414/32,129Reference
 CHPs without LWDHW4,486/20,9620.58 (0.56–0.60)Reference
 LWDHW3,551/16,9450.51 (0.49–0.54)0.86 (0.82–0.90)

Adjusted for sex, age, comorbidity, and number of antidiabetics.