A Metabolomic Investigation of Eugenol on Colorectal Cancer Cell Line HT-29 by Modifying the Expression of APC, p53, and KRAS Genes

Figure 5

Summary of the joint pathway analysis of metabolites and genes using overrepresentation analysis and a hypogeometric test. Circles higher, bigger, and closer to the x-axis are more significant. (1) Aminoacyl-tRNA biosynthesis; (2) valine, leucine, and isoleucine biosynthesis; (3) biotin metabolism; (4) steroid biosynthesis; (5) pantothenate and CoA biosynthesis; (6) glycerolipid metabolism; (7) galactose metabolism; And (8) glutamine and D-glutamate metabolism.