Evaluation of the Effect of Hydroethanolic Root Extract and Solvent Fractions of Cyphostemma adenocaule (Steud. ex A. Rich) Descoings ex Wild & Drummond on Cell-Mediated Immune Response and Blood Cell Count in Mice

Table 3

The effect of controls, hydroethanolic root extract, and solvent fractions of Cyphostemma adenocaule on blood cell count.

Group	Dose (mg/kg)	Blood cell count
		WBC (count ×10^3/mm^3)				RBC (count ×10^6/mm^3)	PLT (count)
		Total	Differentials
			Lym	Mon	Gra
VH	—	4.8367 ± 0.5492	3.5400 ± 0.4469	0.7800 ± 0.879	0.5167 ± 0.0792	9.5467 ± 0.3248	427.6667 ± 62.9929
LEV	50	6.0533 ± 0.4933	4.4600 ± 0.4192	1.0800 ± 0.1352	0.5467 ± 0.1551	10.2180 ± 0.2293	482.5000 ± 47.7317
CYP	30	4.0667 ± 0.4248	2.9333 ± 0.2906	0.7000 ± 0.1592	0.4333 ± 0.0422	9.1500 ± 0.2375	371.0000 ± 4.83046
HEE	100	6.8667 ± 1.0544^c1	4.6000 ± 0.5465	1.4667 ± 0.4295	0.8000 ± 0.1693	10.4870 ± 0.1265^c1	480.5000 ± 6.5727
	200	7.4333^c2 ± 0.2963	4.9500 ± 0.2419^c1	1.6333 ± 0.2044	0.8500 ± 0.0563	10.7750 ± 0.2124^c2	490.3333 ± 9.5592^c1
	400	9.0333 ± 0.0211^a3b1c3g1	6.1667 ± 0.1667^a2c3g1	1.9167 ± 0.1327^a1c2	1.100 ± 0.1414^a1b1c2	10.950 ± 0.1384^a1c3g1	562.3333 ± .6897^a1c3g1
AF	100	5.8750 ± 0.8538	3.9500 ± 0.4660	1.2833 ± 0.3049	0.6417 ± 0.1281	9.8500 ± 0.1088	436.8333 ± 14.5863
	200	6.7000 ± 0.2769	4.5167 ± 0.4308	1.4167 ± 0.1108	0.7667 ± 0.1382	9.9550 ± 0.1938	457.6667 ± 3.3928
	400	7.3333 ± 0.4674^c2	5.1667 ± 0.4609^c1	1.4833 ± 0.0946	0.6833 ± 0.0477	10.4433 ± 0.2372	465.0000 ± 14.509
BF	100	6.5333 ± 0.7247	4.5167 ± 0.5636	1.3333 ± 0.2765	0.7333 ± 0.1022	10.3520 ± 0.2122	464.5000 ± 14.0327
	200	6.8833 ± 0.3772^c1	4.6833 ± 0.3772	1.4167 ± 0.1327	0.7833 ± 0.0910	10.4163 ± 0.2118	473.1667 ± 6.8577
	400	7.9833 ± 1.9104^a2c3	5.2833 ± 0.3868^c2	1.7333 ± 0.1256^c1	0.9667 ± 0.0760^c1	10.7817 ± 0. 2318^c2	498.1667 ± 4.4603^c1

VH = vehicle, LEV = levamisole CYP = cyclophosphamide, HEE = hydroethanolic root extract, AF = aqueous fraction, BF = n-butanol fraction, WBC = white blood cell, Lym = lymphocyte, Mon = monocyte, Gra = granulocyte, RBC = red blood cell, PLT = platelet, a = compared to gum acacia, b = compared to levamisole, c = compared to cyclophosphamide, g = compared to 100 mg/kg aqueous fraction, .