Sex-Biased Gene Expression of Mesobuthus martensii Collected from Gansu Province, China, Reveals Their Different Therapeutic Potentials

Figure 8

Sequence alignment, 3D modeling, and phylogenetic analysis of peroxiredoxin IV;. (a) A putative sequence sequence Trinity_DN19197_c3_g1 is aligned with a model PrxIV (PDB ID: 3QPM). At the bottom of columns, asterisk () represent conserved positions, colons (:) represent conserved substitutions and points (.) represent nonconserved substitutions. Grey lines, green bends, blue-banded arrowheads, and red solenoids represent coils, turns, sheets, and helices, respectively. Different fragments are framed by red lines. (b) 3D modeling was simulated by the template PrxIV (PDB ID: 3QPM) in SWISS-MODEL and viewed in Discovery Studio 2016. The grey, green, blue, and red represent coils, turns, sheets, and helices, respectively. Different structures are indicated with red arrows. (c) Phylogenetic tree was constructed with sequence Trinity_DN19197_c3_g1, which is a putative PrxIV and 10 other sequences from different species, in MEGA 7, by the Neighbor-Joining method. The putative PrxIV is marked in a red dot, arthropoda in light blue dots, brachiopoda in a pink dot, and mollusca in a green dot.

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