Nonclinical Safety Pharmacology Study of the Herbal Product HAD-B1

Table 5

Effects of HAD-B1 on tidal volume (mL) in rats.

Groups	Dose (mg/kg)	Time (hr)
		0	1	2	4	6	24
Control	0	1.23 ± 0.18	1.20 ± 0.15	1.16 ± 0.24	1.15 ± 0.13	1.17 ± 0.20	1.25 ± 0.17
T1	500	1.24 ± 0.07	1.19 ± 0.09	1.14 ± 0.11	1.12 ± 0.07	1.14 ± 0.12	1.27 ± 0.16
T2	1000	1.22 ± 0.17	1.21 ± 0.16	1.18 ± 0.12	1.14 ± 0.11	1.21 ± 0.18	1.34 ± 0.19
T3	2000	1.15 ± 0.14	1.15 ± 0.08	1.13 ± 0.14	1.14 ± 0.20	1.16 ± 0.16	1.26 ± 0.15

Note. Data described as the mean ± S.D. (n = 8).