Research Article

Herb-Partitioned Moxibustion Improves Crohn’s Disease-Associated Intestinal Fibrosis by Suppressing the RhoA/ROCK1/MLC Pathway

Table 1

Criteria for histologic fibrosis scoring.

ScoreDescription

Fibrosis0No increased collagen deposition
1Increased collagen deposition in the submucosa and mucosa
2Increased collagen deposition in the submucosa and mucosa
3Increased collagen deposition in the muscularis mucosa, submucosa, and mucosa; thickening and disorganization of the muscularis mucosa
4Increased collagen deposition in the muscularis propria, muscularis mucosa, submucosa, and mucosa
5Increased collagen deposition throughout all layers, including the serosa

Percent involvement10–25% of the section
225–50% of the section
350–75% of the section
475–100% of the section