Evidence-Based Complementary and Alternative Medicine

Research Article

Exploratory Compatibility Regularity of Traditional Chinese Medicine on Osteoarthritis Treatment: A Data Mining and Random Walk-Based Identification

Table 4

Baseline characteristics of all patients.


Variables		Before matching			After matching
Variables		Control group (n = 7,119)	Experimental group (n = 5,964)	value	Control group (n = 4,438)	Experimental group (n = 4,438)	value

Demographics	Age/year, mean ± SD	58.56 ± 13.71	62.75 ± 12.88	<0.001	60.06 ± 13.84	59.84 ± 12.82	0.068

Sex	Male, n (%)	1,402 (19.69)	1,582 (26.53)	<0.001	907 (20.43)	912 (20.55)	0.072
Sex	Female, n (%)	5,717 (80.31)	4,382 (73.47)	<0.001	3,531 (79.56)	3,526 (79.45)	0.080

Anthropometric measurements	BMI, kg/m²	28.36 ± 5.60	26.56 ± 6.50	<0.001	27.12 ± 6.25	27.68 ± 6.04	0.094

Clinical characteristics	LOS, days, mean ± SD	15.05 ± 7.77	17.10 ± 9.08	<0.001	16.36 ± 8.36	16.49 ± 7.91	0.074

Underlying diseases	Coronary heart disease, n (%)	354 (4.97)	233 (3.91)	<0.001	189 (4.26)	183 (4.12)	0.061
	Hypertension, n (%)	193 (2.71)	1,243 (20.84)	<0.001	193 (4.34)	199 (4.48)	0.056
	Cerebral infarction, n (%)	236 (3.32)	768 (12.88)	<0.001	229 (5.16)	231 (5.21)	0.063
	Diabetes, n (%)	119 (1.67)	610 (10.23)	<0.001	119 (2.68)	132 (2.97)	0.051
	Chronic gastritis, n (%)	1,353 (19.01)	744 (12.47)	<0.001	572 (12.89)	619 (13.95)	<0.001
	Anemia, n (%)	207 (2.91)	167 (2.80)	<0.001	93 (2.10)	133 (3.00)	<0.001
	Osteoporosis, n (%)	1,861 (26.14)	1,616 (27.10)	<0.001	1,214 (27.35)	1,202 (27.08)	0.063
	Fatty liver, n (%)	768 (10.79)	700 (11.74)	<0.001	361 (8.13)	475 (10.70)	<0.001

Index	ESR (mm/h)	28.79 ± 15.89	14.44 ± 11.97	<0.001	30.18 ± 16.92	29.26 ± 12.84	0.112
	CRP (mg/L)	14.44 ± 7.96	27.80 ± 9.26	<0.001	14.66 ± 8.48	16.50 ± 7.12	0.124
	IgA (g/L)	2.35 ± 1.07	2.65 ± 1.25	<0.001	2.38 ± 1.09	2.41 ± 1.21	0.085
	IgM (g/L)	1.26 ± 0.67	1.23 ± 0.72	0.427	1.20 ± 0.63	1.21 ± 0.70	0.354
	IgG (g/L)	12.40 ± 3.99	15.91 ± 4.06	<0.001	12.61 ± 4.04	13.04 ± 4.14	0.214
	C3 (g/L)	83.69 ± 49.72	93.12 ± 53.61	<0.001	97.16 ± 39.22	90.01 ± 54.33	0.359
	C4 (g/L)	26.04 ± 13.44	22.27 ± 14.53	<0.001	23.43 ± 11.69	22.50 ± 14.69	0.212

Note: BMI, body mass index; LOS, length of hospital stay; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; IgA: immunoglobulin A; IgM: immunoglobulin M; IgG: immunoglobulin G; C3: complement C3; C4: complement C4.