Mufangji Decoction and Its Active Ingredient Patchouli Alcohol Inhibit Tumor Growth through Regulating Akt/mTOR-Mediated Autophagy in Nonsmall-Cell Lung Cancer

Figure 3

In vivo and in vitro experiments of patchouli alcohol, an effective ingredient of Mufangji Decoction, on the growth of NSCLC. (a) The effect of different doses of patchouli alcohol on the proliferation of NSCLC cells A549. (b) The effect of different doses of patchouli alcohol on the volume of subcutaneously transplanted NSCLC. (c, d) After the intervention of different doses of patchouli alcohol, the subcutaneously transplanted tumor was surgically removed and the tumor size of each group was weighed. (e) Comparison of the tumor inhibition rate of different doses of patchouli alcohol. PA-L: 5 mg/kg; PA-M: 10 mg/kg; PA-H: 15 mg/kg. Compared with the model group, .

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