Network Pharmacology-Based Prediction of Catalpol and Mechanisms against Stroke

Table 1

Target information and type attribution of catalpol in the treatment of stroke.

Gene name	Protein class
ACE	Hydrolase; protease
PLAU	Hydrolase; protease
BACE1	Hydrolase; protease
F2	Hydrolase; protease
REN	Hydrolase; protease
MMP9	Hydrolase; protease
VDR	Nucleic acid binding; receptor; transcription factor
NR3C2	Nucleic acid binding; receptor; transcription factor
PPARG	Nucleic acid binding; receptor; transcription factor
TGFB2	Signaling molecule
PGF	Signaling molecule
MAPK1	Kinase; transferase
MAPK14	Kinase; transferase
ACADM	Oxidoreductase; transferase
MAPKAPK2	Cytoskeletal protein; kinase; transferase
CBS	Hydrolase; isomerase; lyase
ALB	Transfer/carrier protein
ABO	Transferase
SOD2	Oxidoreductase
IGF1	None
KDR	None
NOS2	None
REG1A	None
JAK2	None
MAP2K1	None
HSD11B1	None
APRT	None